What is Tranquilene?

Tranquilene, an all-natural supplement, helps to reduce anxiety and correct stress-causing nutritional deficiencies over time. It is made from traditional eastern herbs and proven western ingredients. Tranquilene is a tranquilizer that regulates the levels of serotonin, GABA and other neurotransmitters in the body.

What’s Inside Tranquilene?

Tranquility Labs is the manufacturer of this brain health supplement based in Massachusetts. Rob Barry, the founder, was his father a Naturopath. They are experts in natural dietary supplements. The tranquillity laboratory supplements are made in an FDA- and GMP-registered pharmaceutical facility in the USA. It is proud to combine the best of western nutrition science and traditional eastern herbal medicine to offer the highest quality supplements.

Tranquilene Claims

Tranquilene is a holistic anti-anxiety supplement. It claims to provide not only immediate relief but also long-term benefits in correcting nutritional deficiencies. Some of these claims include:

  • Comfort from stress and anxiety
  • Relaxation and mood enhancement naturally
  • Enhancing brain performance and emotional balance
  • Supporting the production of GABA, serotonin and other serotonins
  • Tranquilene Ingredients Analysis

Tranquillity’s principal concept is the combination of eastern and western science. We were intrigued to see the ingredient list. It sounds very promising:

  • Passion Flower
  • GABA
  • L-Tryptophan
  • Ashwagandha
  • Brahmi (Bacopa Monnieri)
  • L-Theanine
  • Green tea extract
  • Calcium Carbonate
  • Vitamin D3
  • B Vitamins
  • Magnesium Citrate

Passion Flower

The climbing vine plant Passionflower is native to America. It is used to treat anxiety and sleep problems. This plant’s oral intake is known to increase GABA levels, which can help reduce stress. A study published in Phytotherapy Review found that participants who were given passionflower tea for 7 days experienced a decrease in anxiety and decreased sleep disturbances. The National Centre for Complementary and Integrative Health found that passiflora can cause confusion and dizziness. Passiflora reduces brain activity and induces sleep so it is not recommended to be consumed before driving.


Gamma-aminobutyric or GABA, is an amino acid found naturally in the human body. It acts as an inhibitory neurotransmitter, which blocks stress-related signals. Yet, no conclusive scientific studies have been done on GABA. Frontiers in Psychology published a study that emphasized the need to conduct more scientific research on GABA’s long-term effects and the way it works.

The key point: GABA supplements are often associated with upset stomachs, headaches, sleepiness, muscle weakness, and sleepiness.


Tryptophan, an essential amino acid, is well-known to aid in the production of serotonin. Protein-rich foods like chicken, eggs and fish are a good source of Tryptophan. Natural Tryptophan is a good source. It is believed to promote sleep and relief from anxiety.

Side effects of taking it as a supplement may include nausea, heartburn, vomiting, and stomach pain. The National Organization for Rare Disorders published a report on a rare condition caused by Tryptophan supplement consumption, known as eosinophilia myalgia syndrome (EMS). In 1980, 37 people died from this disease. It may also increase serotonin levels beyond what is necessary, particularly if it is taken with other serotonin-enhancing medications. Because of its ties with EMS, it may also cause liver and kidney disease. According to scientific studies, this ingredient could be dangerous to consume.


Ashwagandha, an ancient herbal treatment used in Ayurveda to treat various ailments, is a significant and important herb. There are many benefits to Ashwagandha, including improving brain health, energy levels, and concentration. Although there have not been any long-term studies on this herb, they are generally safe for healthy people to consume. It should be avoided by pregnant and nursing women as well as people suffering from autoimmune diseases.

Brahmi (Bacopa Monnieri)

Bacopa, an ayurvedic herb, has been used for centuries to improve memory, stress relief, and focus. Research has shown that it can improve learning retention and performance.


Theanine is an amino acid found in tea leaves that can help reduce anxiety and stress. Studies have shown that it has a positive effect on mental alertness (1). MDPI published a report that supports Theanine’s anti-stress properties. It is also known to promote relaxation and prevent drowsiness (1).

Green Tea Extract

The purpose of green tea extract is to provide immediate stimulation for the brain. It can also improve mood and mental alertness. Research shows that caffeine can have no side effects if taken in small quantities. Over-stimulation can occur if you consume too much caffeine.

Calcium Carbonate

Calcium deficiency can lead to weaker bones which can cause muscle tension and stress. While essential for the normal functioning of your body, we recommend that you consult a doctor and have tests done to determine if there are any deficiencies. Too much calcium can lead to nausea, vomiting, constipation and confusion. The body may be affected by medicine interference. Calcium can make it harder to absorb other medicines.

Vitamin D3

Vitamin D is vital for bone health. It helps to absorb calcium. Vitamin D is also important in the prevention of heart disease and maintaining a healthy blood pressure. Vit D oral intake does not pose any dangers if it is taken in the recommended dosage. Consuming Vit D in higher doses can increase the risk of calcium build-up in the blood.

B Vitamins

B-vitamins, essential micronutrients, perform vital functions in the body. They help maintain good health and brain performance. They aid the body in the processing of nutrients and the conversion of food into energy. Each B vitamin has a specific role in the body. Research has shown that small amounts of B-complex have no side effects for the body.

Magnesium Citrate

Magnesium, another important mineral, is also found in the human body. Magnesium is used to treat constipation and as a laxative. If you are experiencing nausea, kidney disease, or stomach pains, consult your doctor before taking a magnesium supplement.

Are Tranquilene Ingredients Safe & Effective?

Supplement safety is paramount. Tranquility Labs contains powerful nootropics to improve brain function. Bacopa and Ashwagandha, as well as L-Theanine, are all active ingredients that can help with brain health and emotional distress. They have been subject to many clinical trials. Bacopa and Ashwagandha, potent herbs that can improve memory and focus, have been used for centuries. Tryptophan is our only concern. Because of its effectiveness, it is one of the most important ingredients in Tranquilene.
There are serious safety concerns. If you’re considering allowing it to be used, we recommend that you consider its possible side effects.

  • Drowsiness
  • Fatigue
  • Stomach upset
  • Headache
  • Morning grogginess
  • Sedative drugs have more powerful effects
  • Blood pressure can be lowered

There was no evidence to support the inclusion of calcium, vitamin D and magnesium in a nootropic formulation. However, it does help with overall bone and muscle health. This may indirectly link to stress reduction.

Warnings to Tranquilene Users

According to the official website, pregnant or nursing women should consult a doctor before using Tranquilene. If you take blood thinners, muscle relaxants or any other pain-relieving and sedative medications, drug interaction may occur.

How do you use Tranquilene?

According to the official website, two tablets per day should be taken with water. One in the morning, one in the afternoon.

Does Tranquilene Provide 100% BrainPower?

Tranquilene is a stress-relieving agent that increases serotonin, GABA and reduces stress. This may lead to a happier brain and calmer mind. Bacopa and Ashwagandha, two nootropics, have been used for centuries to improve memory, focus, learning, and other aspects. While this is a wonderful formula, it would have been even more effective and potent if there were some other essential ingredients. One such ingredient is the Lion’s Mane mushroom, which has shown invariable positive results supporting brain health through stimulating the New Growth Factor Product. It is also missing L-Tyrosine which is a powerful element that works with neurotransmitters to aid with memory, mood and mental processing. It’s a good formula overall, but it could have been more compelling if it had a few additional ingredients.

Where can you buy Tranquilene?

You can purchase Tranquilene from their official website or Amazon :

  • A 60-caps Tranquilene bottle costs $ 42.5

Return Policy & Money-Back Guarantee

If the bottles are not opened within 60 days of purchase, the company will issue a full refund.

Is Tranquilene A Good Nootropic For You?

Tranquilene, a powerful supplement, has been shown to reduce stress and anxiety. These ingredients work together to calm your mind and increase brain productivity. As we have said, it is important to research the subject of Tryptophan before you decide to add it to your daily supplements .If you’re looking for a safer option that comes with a scientifically-backed ingredients list, then we suggest you consider one of the best nootropics available, Mind Lab Pro. Mind Lab Pro is packed with powerful ingredients such as Rhodiola Rosea and Lion’s Mane mushroom. These are well-known for their stress-busting properties and cognitive-enhancing abilities. Read our full review of the product.


Our research shows that Tranquilene supports some of its claims. Although we love the use of herbs such as Ashwagandha and Bacopa, it could have been more potent if there were more essential nootropics. However, mixed reviews exist regarding the safety and efficacy of Tryptophan. This is a deal-breaker for us. Mind Lab Pro is a nootropic that works without side effects and can be used by anyone who needs it. Mind Lab Pro is a 100% vegan nootropic that is free of additives. Want to know more?

By Stevie

I'm the owner of and a part time personal trainer, part time writer. This website is where i impartially review supplements and other healthcare products. I'll try and get scientific without being completely overwhelming. Hence...'sub atomic'...

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